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Research Use Only18+Not for Human ConsumptionReconstitution Materials Not Supplied
Peptide Database

Cognitive & neurological research

Adalank (N-Acetyl Selank Amidate): Research Overview

Chemically modified form of Selank studied in anxiety and cognition research.

Also known as N-Acetyl Selank Amidate · NA-Selank Amidate

Research use onlyStrongest evidence: animal studyReviewed
DatabaseReferences

What is Adalank?

Enhanced derivative of Selank with improved stability, blood-brain barrier penetration, and extended half-life compared to parent compound. Parent compound Selank approved in Russia since early 2000s.

What is Adalank researched for?

  • Clinical trials showed effects comparable to benzodiazepines; 40% rapid response within 1-3 days.
  • Reduces stress hormones and balances neurotransmitters without sedation.
  • Unlike benzodiazepines, provides relief without tolerance, withdrawal, or dependency.
  • Improves focus, attention, and mental clarity.
  • BDNF-mediated neuroplasticity supports memory formation.
  • Rapidly elevates BDNF expression, supporting neuronal survival.
  • Enhances ability to cope with psychological stress.

How does Adalank work?

Modulates GABAergic neurotransmission, upregulates hippocampal BDNF, influences serotonin metabolism, and provides immunomodulatory effects without benzodiazepine-like dependency.

References

  1. Selank for GAD - Non-inferiority Trial

    62 patients with GAD; 2700mcg/day intranasal; 14 days. Anxiolytic effects comparable to medazepam; 40% rapid response within 1-3 days.

  2. Selank and BDNF Regulation in Hippocampus

    Rat study; intranasal administration. Rapidly elevated BDNF expression, confirming neurotrophin involvement.

    Animal study

  3. Peptide Selank Enhances Diazepam Effects

    Rats in chronic mild stress model. Enhanced anxiolytic effects while reducing memory impairment and sedation.

    Animal study

Common questions

What's the difference between Adalank and regular Selank?

Adalank is an N-acetyl form with C-terminal amidation, providing enhanced stability, better blood-brain barrier penetration, and extended half-life compared to parent compound Selank. This makes Adalank more potent and longer-acting while retaining the same anxiolytic and BDNF-upregulating mechanisms.